A tissue transglutaminase (tTG) test is a blood test that measures IgA antibodies to help diagnose coeliac disease, an autoimmune disorder triggered by gluten. It works by detecting antibodies the body produces in response to gluten, which mistakenly attacks the enzyme tissue transglutaminase in the small intestine. Elevated levels can indicate coeliac disease, and the test is recommended for those with symptoms like diarrhea, bloating, and fatigue, or for individuals with a family history of the condition.
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