A syphilis total antibodies test (like SYPHT) detects all antibodies to the syphilis bacterium (Treponema pallidum), usually as a screening step; a positive result means past or present infection but needs a confirmatory nontreponemal test (like RPR/VDRL) and potentially a treponemal-specific test (like TP-PA) to tell if it's active, as it stays positive even after treatment, but negative results can happen in very early or late stages, requiring clinical context for
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