A pseudo cholinesterase serum test measures the enzyme's activity in blood, primarily to diagnose and monitor organophosphate (OP) insecticide poisoning, as low levels indicate exposure and help predict severity, guiding treatment like atropine. While the enzyme itself isn't inhibited by OPs, its decrease reflects the overall cholinergic crisis, with lower levels correlating to worse outcomes (longer ICU stays, higher mortality). The test helps assess exposure, monitor recovery, and manage care, though red blood cell AChE levels often better reflect central nervous system effects.
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