formed via peripheral blood smear (PBS), helps identify red blood cell (RBC) fragments, called schistocytes, which can indicate thrombotic microangiopathy (TMA) or other conditions. Schistocytes are RBC fragments with sharp angles, straight edges, or crescent shapes. A percentage of schistocytes greater than 1% on a PBS, in the absence of other significant RBC abnormalities, is a key criterion for diagnosing TMA.
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