The PR3-ANCA (c-ANCA) test is a blood test measuring antibody levels that target the proteinase 3 (PR3) enzyme in neutrophils to diagnose and monitor autoimmune small-vessel vasculitis, specifically Granulomatosis with Polyangiitis (GPA). High levels suggest active disease (e.g., inflammation in kidneys, lungs), while declining levels indicate effective treatment.
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