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The PLA2R Antibody (Quantitative, Serum) test measures the precise level of antibodies targeting the M-type phospholipase A2 receptor in the blood. It is a highly specific, non-invasive blood test used to diagnose and monitor Primary Membranous Nephropathy (pMN), a cause of nephrotic syndrome. High levels often correlate with disease activity, helping guide immunosuppressive therapy.