HAEMAGGLUTINATION (T

The TPHA (Treponema Pallidum Hemagglutination) test is a blood test used to diagnose syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It detects antibodies produced by the body in response to the bacteria. The test is valuable for confirming a syphilis infection, especially when other tests are inconclusive or when symptoms are not immediately apparent, according to Apollo 24|7.
Here's a more detailed explanation:
What it detects: The TPHA test detects antibodies against Treponema pallidum, the bacteria that causes syphilis, in a patient's blood sample.
How it works: The test utilizes the principle of hemagglutination. Red blood cells are sensitized with fragments of T. pallidum. If the patient's blood sample contains antibodies against T. pallidum, these antibodies will bind to the sensitized red blood cells, causing them to clump together (agglutinate) on a test dish.